Promising new therapeutic strategy for Parkinson’s Disease

A new research project at SITraN investigates the potential of drugs that rescue axonal transport defects in Parkinson’s disease to keep nerve cells from dying. Following on from their promising research published recently in Nature Communications, researchers Dr Kurt De Vos from SITraN and his collaborator Dr Alex Whitworth from the Department of Biomedical Sciences…

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Build-up of DNA damage in nerve cells can lead to dementia

Scientists from the Sheffield Institute for Translational Neuroscience (SITraN) have discovered a novel pathway contributing to dementia in individuals that lack the typical signs of Alzheimer’s disease in the brain. The research published now in the journal Neuropathology and Applied Neurobiology builds on previous work using brain tissue donated to the Medical Research Council Cognitive…

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Ambitious research project trials promising new therapy for motor neurone disease

Researchers from the University of Sheffield‘s Institute for Translational Neuroscience (SITraN) are involved in an ambitious European research project aimed at finding a new treatment for motor neuron disease (MND). The collaboration between world-leading academic research groups aims to identify the therapeutic potential of a molecule (interleukin-2) that occurs naturally in our bodies and helps…

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