Title: “Genetic control for therapy: synthetic transcription repressors in Huntington’s disease” Venue: Rooms B02/B03, SITraN, 385a Glossop Road, Sheffield S10 2HQ Speaker: Dr Mark Isalan, Faculty of Natural Sciences, Department of Life Sciences, Imperial College, London   Background Dr Mark Isalan is a Reader in Gene Network Engineering at Imperial College London and runs a research group…

Title: “Intron retention and nuclear loss of Splicing Factor Proline and Glutamine rich (SFPQ) are hallmarks of ALS” Venue: Rooms B02/B03, SITraN, 385a Glossop Road, Glossop Road, Sheffield S10 2HQ Speaker: Dr Rickie Patani, MRC Senior Clinical Fellow. The Francis Crick Institute, London Biography Rickie Patani obtained a BSc (in Cellular and Molecular Neuroscience) and…

Title: “A multifaceted approach to disease mechanisms in common and rarer forms of Parkinsonism” Venue: Rooms B02/B03, SITraN, 385a Glossop Road, Glossop Road, Sheffield S10 2HQ Speaker: Dr George Tarforis, Associate Professor and Honorary Consultant Neurologist, University of Oxford Background My research aim is to delineate cellular pathways in protein quality control that could inform the development…