Department of Infection, Immunity & Cardiovascular Disease Seminar Series

Dr. John Blaikley

Wednesday 26th June 2019

Title:  “Regulation of lung pathophysiology via circadian control of Integrinβ1 and RhoA”
Speaker:  Dr. John Blaikley, University of Manchester.
Venue:  Lecture Theatre 3, F Floor Medical School.
Time: 12:30pm – 1:30pm
Abstract:  In 2017 the Nobel Prize was awarded to researchers who discovered the circadian clock. It is now recognised that this clock alters 40% of known biological pathways; however the relevance of this clock and circadian biology to human pathophysiology is poorly understood. John Blaikley is a MRC clinician scientist investigating how the “clock” regulates pathophysiology in the lung. He has recently published papers showing that acute lung injury, asthma and wound healing are all under circadian control. Currently he is investigating the role of circadian biology in pulmonary fibrosis and pneumonia. During this talk he will discuss the translational relevance of pulmonary circadian biology and how its investigation can lead to novel therapeutic interventions.


Dr. Helder Nakaya

Thursday 18th July 2019

Title:  “Recent Advances in Network Medicine”
Speaker:  Dr. Helder Nakaya, University of Sao Paulo, Brazil.
Venue: Lecture Theatre 3, F Floor Medical School.
Time:  12:30pm – 1:30pm
Abstract:  Diseases are mostly a consequence of an abnormality in multiple genes. Network Medicine investigates how genes interact to each other in complex intracellular and intercellular networks. The talk will show the recent advances on this emerging field of research and its impact on precision medicine and drug repositioning.


For enquiries, please contact iicd@sheffield.ac.uk