SITraN Lunchtime Seminar: Monday 08 April, 13:00 – 14:00: Dr Rickie Patani, The Francis Crick Institute, London

Title: “Intron retention and nuclear loss of Splicing Factor Proline and Glutamine rich (SFPQ) are hallmarks of ALS”

Venue: Rooms B02/B03, SITraN, 385a Glossop Road, Glossop Road, Sheffield S10 2HQ

Speaker: Dr Rickie Patani, MRC Senior Clinical Fellow. The Francis Crick Institute, London

Rickie Patani obtained a BSc (in Cellular and Molecular Neuroscience) and MBBS from Imperial College London in 2004. He gained MRCP (UK) in 2007 and a PhD in Stem Cell Neurobiology from Cambridge University in 2011, funded by a Wellcome Trust Clinical Research Fellowship. While completing his higher clinical training in Neurology, he was awarded a Wellcome Trust Intermediate Clinical Fellowship to start his independent research group at UCL Queen Square Institute of Neurology from 2013. Rickie gained MRCP (Neurology) in 2015 and was subsequently appointed Honorary Consultant Neurologist at the National Hospital for Neurology, Queen Square. Rickie was appointed Group Leader at the Francis Crick Institute in 2016, where his research group continue to work on human induced pluripotent stem cell models of motor neuron disease (ALS), with particular focus on the themes of RNA metabolism and cellular autonomy. He was appointed Associate Professor at UCL Queen Square Institute of Neurology in 2017, and subsequently elected Fellow of the Royal College of Physicians (FRCP). In 2018, Rickie was awarded an MRC Senior Clinical Fellowship to continue his group’s work on the cellular and molecular mechanisms underlying ALS. The Patani lab has a diverse portfolio of public engagement activities (see the group’s twitter account @PataniLab for more information).