The Mellanby Centre for Bone Research Seminar – Innovation versus Evidence: Are these conflicting objectives?

Professor Rob Nelissen*, Leiden University Medical Centre (LUMC), South Holland

Friday, 22 February 2019, 12.30 – 1.30

Lecture Theatre 3, F Floor, Medical School


Can technology-driven practice innovation go hand in hand with evidence-based medicine? For example, pelvic osteosarcoma reconstruction often requires bespoke printed implants and material innovation is promoted to tackle increasing antibiotic resistance of prosthetic infections. However, these new technologies may also have less favourable outcomes. In this lecture I will explore how comprehensive partnership in international data capture and reporting of activity and outcomes might be applied to optimise innovation in orthopaedics, be ally for surgeons, and an asset for patients.


Rob Nelissen is Professor and Chairman of the Department of Orthopaedics, Leiden University Medical Center (LUMC). Title doctorate thesis (1995): ‘Fundamental aspects of the clinical evaluation of total joint prosthesis’. After his orthopaedic training (Leiden), he finished a Total Joint Fellowship in the USA (1993), in 2005 Professor Experimental Orthopaedics,.in 2006 Chairman and Professor Orthopaedics LUMC and in 2016 Medical Delta Professor at Delft University of Technology, Department of Biomechanical Engineering. He was president of the Netherlands Orthopaedic Association (2016-2018). He is the co-founder, current Chairman of the Dutch Arthroplasty Register (LROI) which is the third largest implant registry worldwide (> 670.000 implants, completeness 99%). The LROI is a quality and traceability Register of implant surgery and patient outcome. He is Chairman of N.O.R.E. (Network Orthopaedic Registries of Europe) an EFORT (European Federation Orthopaedics) committee. He initiated and performs healthcare evaluation programs. He is steering group member of the OECD on patient outcome with hip and knee implants. He published over 250 peer-reviewed articles, with focus on healthcare evaluation and prognostic modeling and optimizing outcome in arthroplasty patients. He has supervised over 30 PhD students in the past and is currently supervisor for 10 PhD students.