The 3rd Annual Florey Institute Postgraduate Symposium took place on Friday 24th June. Postgraduate students and early career researchers with an interest in host-pathogen interactions and antimicrobial resistance involving, but not limited to, research on S. aureus and S. pneumoniae joined together for this one-day symposium. The following students from the Department of Infection, Immunity & Cardiovascular Disease were successful in being awarded prizes for their poster presentations.
Andreea Cinutu – 3rd Year PhD Student
Staphylococcus aureus is a highly opportunistic pathogen and the cause of significant morbidity and mortality. Neutrophils are a critical cellular defense during infection, however S. aureus has employed multiple mechanisms to evade neutrophilic immunity. Understanding the host-pathogen interaction is of key priority in order to develop novel therapeutics for S. aureus infection. Andreea has found that the tetraspanin, CD151, is involved in the entry of S. aureus into human neutrophils and won the first prize at the 2016 Florey Symposium for my poster presentation of this work.
Roxanne Lau – 3rd Year PhD Student
Roxanne is working on the flap endonuclease (FEN) domain of the Streptococcus pneumoniae DNA polymerase I enzyme, an essential component of the DNA replication machinery. She has recently determined the structure of the streptococcal FEN interacting with its DNA substrate. The work will aid towards the development of new antibiotics via structure-based drug design in the future. Roxanne received second prize for her poster at the 2016 Florey Symposium.