Build-up of DNA damage in nerve cells can lead to dementia

Scientists from the Sheffield Institute for Translational Neuroscience (SITraN) have discovered a novel pathway contributing to dementia in individuals that lack the typical signs of Alzheimer’s disease in the brain. The research published now in the journal Neuropathology and Applied Neurobiology builds on previous work using brain tissue donated to the Medical Research Council Cognitive…

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Ambitious research project trials promising new therapy for motor neurone disease

Researchers from the University of Sheffield‘s Institute for Translational Neuroscience (SITraN) are involved in an ambitious European research project aimed at finding a new treatment for motor neuron disease (MND). The collaboration between world-leading academic research groups aims to identify the therapeutic potential of a molecule (interleukin-2) that occurs naturally in our bodies and helps…

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