A Novel Regulator, which Directs Development of Vascular Disease

Researchers at the University of Sheffield have demonstrated that a regulator, which controls enhanced inflammatory responses, is central to development of cardiovascular disease. The IL-1RI co-receptor TILRR, originally identified by Professor Qwarnstrom’s group, is present at high levels within affected areas of the vessel where it amplifies activation of inflammatory cells, leading to a worsening…

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Celebrating Speech and Language Therapy

The Department of Human Communication Sciences (HCS), in partnership with the  Royal College of Speech and Language Therapists (RCSLT) and the Sheffield Speech and Language Therapy services held an event on July 11th 2017 to celebrate Speech and Language Therapy in Sheffield and the wider region. Over 100 speech and language therapists (SLTs) and SLT…

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MRI method detects progression of lung disease in children with Cystic Fibrosis before normal clinic

Researchers from POLARIS and clinical colleagues from Sheffield Children’s Hospital have shown that using a technique called ‘hyperpolarised gas MRI’, it is possible to measure the progression of lung disease in children with cystic fibrosis (CF), before the normal clinical tests can detect this progression. Hyperpolarised gas MRI requires the participant to breathe in a…

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A new study identifies genes involved in white blood cell biology

An MRC funded project led by researchers in Infection, Immunity and Cardiovascular Disease has culminated in a publication in the journal, Blood, which identifies genes that regulate leukocyte production and function. Neutrophils, our most abundant leukocyte, are critical in fighting infection and responding to inflammation. Defects in neutrophil production and function can lead to devastating…

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